TATA Ex Next Generation 1.5 Accounting 25 ((HOT))

The 300 MWe AHWR will have vertical pressure tubes in which the light water coolant under high pressure will boil at 285C, circulation being by convection. Thermal efficiency is 30.9%. It is moderated by heavy water. There are 452 fuel assemblies, with burn-up of 38 GWd/t. A large heat sink or "gravity-driven water pool" with 7000 cubic metres of water is near the top of the reactor building and has a safety function. It has a slightly negative void coefficient of reactivity and several advanced passive safety features to enable meeting next-generation safety requirements such as 72-hour grace period for operator response, elimination of the need for exclusion zone beyond the plant boundary, 100-year design life, and high level of fault tolerance. The advanced safety characteristics have been verified in a series of experiments carried out in full-scale test facilities. It is claimed that per unit of energy produced, the amount of long-lived minor actinides generated is nearly half of that produced in current generation light water reactors. A high level of radioactivity in the fissile and fertile materials recovered from the used fuel of the AHWR, and their isotopic composition, preclude the use of these materials for nuclear weapons*.

TATA Ex Next Generation 1.5 Accounting 25

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In 2011 FBTR was given a 20-year lifetime extension, to 2030, and IGCAR said that its major task over this period would be large-scale irradiation of the advanced metallic fuels and core structural materials required for the next generation fast reactors with high breeding ratios (the PFBR uses MOX fuel, but later versions will use metal.).

Next generation sequencing: FoundationOneHEME assay is a next generation sequencing (NGS) assay that uses a hybrid capture methodology and detects base substitutions, insertions, deletions, and copy number (CN) alterations in up to 406 genes and gene rearrangements in up to 265 genes, tumor mutation burden and microsatellite instability using the previously described methods [12]. DNA and RNA was extracted using the Maxwell Tissue DNA Purification Kit (Promega AS1030). Library construction was done using NEBNext kits (NEB E6040S) and the sequencing was performed on a HiSeq2500 according to clinical laboratory standards with 150-base pair paired-end reads (Department of Pathology and Molecular Pathology, University Hospital Zurich, Switzerland).